NARILIS seminar by post-doc researcher Anaïs Wanet - Harvard Stem Cell Institute

  • When Sep 07, 2018 from 02:00 PM to 03:00 PM (Europe/Brussels / UTC200)
  • Where UNamur, L12 auditorium
  • Contact Name
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The Laboratory of Cellular and Molecular Biology (URBC) of the UNamur and NARILIS have the great pleasure to invite you to a seminar given by

Dr. Anaïs Wanet

Post-doc researcher
Harvard Stem Cell Institute
Beth Israel Deaconess Medical Center
Daniel G. Tenen lab

Beyond Epithelial Tissues: Investigating E-cadherin Function in Hematopoiesis and Leukemia

DNA methylation analyses revealed frequent methylation of the E-cadherin promoter in patients suffering from leukemia. While the function of this protein is mainly described in epithelial tissues and tumors, its function in the blood is unknown. Single cell RNA-seq revealed expression of E-cadherin in several hematopoietic populations. Our studies focus on the characterization and function of E-cadherin expression during normal hematopoiesis and its deregulation in acute myeloid leukemia.