Radiobiology & protontherapy


Heuskin AC, Gallez B, Feron O, Martinive P, Michiels C, Lucas S. Metallic nanoparticles irradiated by low energy protons for radiation therapy: are there significant physical effects to enhance the dose delivery? Med Phys. 2017 May 23.


Li S, Penninckx S, Karmani L, Heuskin AC, Watillon K, Marega R, Zola J, Corvaglia V, Genard G, Gallez B, Feron O, Martinive P, Bonifazi D, Michiels C, Lucas S. LET-dependent radiosensitization effects of gold nanoparticles for proton irradiation. Nanotechnology. 2016 Nov 11;27(45):455101.

Heuskin AC, Osseiran AI, Tang J, Costes SV. Simulating Space Radiation-Induced Breast Tumor Incidence Using Automata. Radiat Res. 2016 Jul;186(1):27-38.

Karmani L, Levêque P, Bouzin C, Bol A, Dieu M, Walrand S, Vander Borght T, Feron O, Grégoire V, Bonifazi D, Michiels C, Lucas S, Gallez B. Biodistribution of (125)I-labeled anti-endoglin antibody using SPECT/CT imaging: Impact of in vivo deiodination on tumor accumulation in mice. Nucl Med Biol. 2016 Mar 29;43(7):415-423.


Lucas S, Feron O, Gallez B, Masereel B, Michiels C, Vander Borght T. Monte Carlo Calculation of Radioimmunotherapy with (90)Y-, (177)Lu-, (131)I-, (124)I-, and (188)Re-Nanoobjects: Choice of the Best Radionuclide for Solid Tumour Treatment by Using TCP and NTCP Concepts. Comput Math Methods Med. 2015;2015:284360.

Riquier H, Abel D, Wera AC, Heuskin AC, Genard G, Lucas S, Michiels C. Effects of Alpha Particle and Proton Beam Irradiation as Putative Cross-Talk between A549 Cancer Cells and the Endothelial Cells in a Co-Culture System. Cancers (Basel). 2015 Mar 18;7(1):481-502.


Daisne JF, Installé J, Bihin B, Laloux M, Vander Borght T, Mathieu I, Lawson G. SPECT/CT lymphoscintigraphy of sentinel node(s) for superselective prophylactic irradiation of the neck in cN0 head and neck cancer patients: a prospective phase I feasibility study. Radiat Oncol. 2014 May 28;9:121.

Heuskin AC, Michiels C, Lucas S Low dose hypersensitivity following in vitro cell irradiation with charged particles: Is the mechanism the same as with X-ray radiation? International journal of radiation biology 2014, 90:81-89.

Gontard LC, Fernandez A, Dunin-Borkowski RE, Kasama T, Lozano-Perez S, Lucas S Transmission electron microscopy of unstained hybrid Au nanoparticles capped with PPAA (plasma-poly-allylamine): Structure and electron irradiation effects. Micron (Oxford, England : 1993) 2014, 67:1-9.

Vadhavkar, N., Pham, C., Georgescu, W., Deschamps, T., Heuskin, A.-C., Tang, J., Costes, S.V. Combinatorial DNA damage pairing model based on x-ray-induced foci predicts the dose and LET dependence of cell death in human breast cells (2014) Radiation Research, 182 (3), pp. 273-281.


Wera AC, Heuskin AC, Riquier H, Michiels C, Lucas S Low-LET proton irradiation of A549 non-small cell lung adenocarcinoma cells: dose response and RBE determination. Radiation research 2013, 179:273-281.

Heuskin AC, Wera AC, Riquier H, Michiels C, Lucas S Low-Dose Hypersensitivity and Bystander Effect are Not Mutually Exclusive in A549 Lung Carcinoma Cells after Irradiation with Charged Particles Radiation research 2013, 180:491-498.

Riquier H, Wera AC, Heuskin AC, Feron O, Lucas S, Michiels C Comparison of X-ray and alpha particle effects on a human cancer and endothelial cells: survival curves and gene expression profiles Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2013, 106:397-403.

Heuskin AC, Michiels C, Lucas S Toward computer simulation of high-LET in vitro survival curves Physics in medicine and biology 2013, 58:6495-6510.


Wéra AC, Borlon C, Nuttens VE, Riquier H, Feron O, Michiels C, Lucas S. Comparison of the clonogenic survival of A549 non-small cell lung adenocarcinoma cells after irradiation with low-dose-rate beta particles and high-dose-rate X-rays. Int J Radiat Biol. 2012 Mar;88(3):253-7.


A.-C. Wéra, H. Riquier, A.-C. Heuskin, C. Michiels, S. Lucas. In vitro irradiation station for broad beam radiobiological experiments. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Volume 269, Issue 24, 15 December 2011, Pages 3120–3124

A.-C. Heuskin, A.-C. Wéra, H. Riquier, C. Michiels, A. Bulgheroni, M. Jastrzab, M. Caccia, S. Lucas. On the comparison of three methods of assessing beam quality for broad beam in vitro cell irradiation. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Volume 269, Issue 24, 15 December 2011, Pages 3132–3136

V.Nuttens, E.Nahum and S. Lucas. An NTCP Analysis of Urethral Complications from Low Doserate Mono- and Bi-Radionuclide Brachytherapy. Prostate Cancer. Volume 2011 (2011), Article ID 128360, 9 pages.