Coronavirus

Publications

2021

Blairon L, Cupaiolo R, Piteüs S, Beukinga I, Tré-Hardy M. The challenge of screening SARS-CoV-2 variants of concern with RT-qPCR: One variant can hide another. J Virol Methods. 2021 Jul 29:114248.

Favresse J, Douxfils J. Importance of Sample Dilution in the Evaluation of the Antibody Response after SARS-CoV-2 Vaccination. J Infect. 2021 Jul 4:S0163-4453(21)00327-3.

Favresse J, Bayart JL, Mullier F, Elsen M, Eucher C, Eeckhoudt SV, Roy T, Wieers G, Laurent C, Dogné JM, Closset M, Douxfils J. Antibody titers decline 3-month post-vaccination with BNT162b2. Emerg Microbes Infect. 2021 Jul 7:1-8.

Godon A, Durand Z, Agier L, Lecompte T, Mullier F, Marlu R, de Maistre E, Tacquard C, Levy JH, Godier A, Susen S, Albaladejo P. Comparison of Fibrin Monomers and D-dimers to predict thrombotic events in critically ill patients with COVID-19 pneumonia: A retrospective study. Thromb Res. 2021 Jun 19;205:8-10.

Bayart JL, Morimont L, Closset M, Wieërs G, Roy T, Gerin V, Elsen M, Eucher C, Van Eeckhoudt S, Ausselet N, David C, Mullier F, Dogné JM, Favresse J, Douxfils J. Confounding Factors Influencing the Kinetics and Magnitude of Serological Response Following Administration of BNT162b2. Microorganisms. 2021 Jun 21;9(6):1340.

Tré-Hardy M, Cupaiolo R, Wilmet A, Beukinga I, Blairon L. Waning antibodies in SARS-CoV-2 naïve vaccinees: results of a three-month interim analysis of ongoing immunogenicity and efficacy surveillance of the mRNA-1273 vaccine in healthcare workers. J Infect. 2021 Jun 20:S0163-4453(21)00314-5.

Dellicour S, Linard C, Van Goethem N, Da Re D, Artois J, Bihin J, Schaus P, Massonnet F, Van Oyen H, Vanwambeke SO, Speybroeck N, Gilbert M. Investigating the drivers of the spatio-temporal heterogeneity in COVID-19 hospital incidence-Belgium as a study case. Int J Health Geogr. 2021 Jun 14;20(1):29.

Blairon L, Cupaiolo R, Thomas I, Piteüs S, Wilmet A, Beukinga I, Tré-Hardy M. Efficacy comparison of three rapid antigen tests for SARS-CoV-2 and how viral load impact their performance. J Med Virol. 2021 May 29.

Douxfils J, Favresse J, Dogné JM, Lecompte T, Susen S, Cordonnier C, Lebreton A, Gosselin R, Sié P, Pernod G, Gruel Y, Nguyen P, Vayne C, Mullier F. Hypotheses behind the very rare cases of thrombosis with thrombocytopenia syndrome after SARS-CoV-2 vaccination. Thromb Res. 2021 Jul;203:163-171.

Hardy M, Michaux I, Dive A, Lecompte T, Mullier F. Could Daily Monitoring of Fibrin Related Markers Help Suspect a Thrombotic Event in COVID-19 Patients? A Prospective Pilot Study. TH Open. 2021 May 12;5(2):e152-e154.

Bonil L, Lingas G, Coupeau D, Lucet J-C, Guedj J, Visseaux B, Muylkens B. Survival of SARS-CoV-2 on Non-Porous Materials in an Experimental Setting Representative of Fomites. Coatings. 2021; 11(4):371.

Favresse J, Bayart JL, Mullier F, Dogné JM, Closset M, Douxfils J. Early antibody response in healthcare professionals after two doses of SARS-CoV-2 mRNA vaccine (BNT162b2). Clin Microbiol Infect. 2021 May 8:S1198-743X(21)00224-X.

Bareille M, Hardy M, Douxfils J, Roullet S, Lasne D, Levy JH, Stépanian A, Susen S, Frère C, Lecompte T, Mullier F. Viscoelastometric Testing to Assess Hemostasis of COVID-19: A Systematic Review. J Clin Med. 2021 Apr 16;10(8):1740.

Tré-Hardy M, Cupaiolo R, Papleux E, Wilmet A, Horeanga A, Antoine-Moussiaux T, Vecchia AD, Beukinga I, Vekemans M, Blairon L. Reactogenicity, safety and antibody response, after one and two doses of mRNA-1273 in seronegative and seropositive healthcare workers. J Infect. 2021 Aug;83(2):237-279.

Favresse J, Douxfils J. Evaluations of SARS-CoV-2 serological assays performance need inclusion of long-term samples. J Clin Microbiol. 2021 May 19;59(6):e00487-21.

Favresse J, Cadrobbi J, Eucher C, Elsen M, Laffineur K, Dogné JM, Douxfils J. Clinical performances of three fully automated anti-SARS-CoV-2 immunoassays targeting the nucleocapsid or spike proteins. J Med Virol. 2021 Apr;93(4):2262-2269.

Favresse J, Eucher C, Elsen M, Gillot C, Van Eeckhoudt S, Dogné JM, Douxfils J. Persistence of Anti-SARS-CoV-2 Antibodies Depends on the Analytical Kit: A Report for Up to 10 Months after Infection. Microorganisms 2021 Mar 8;9(3):556.

Haguet H, Douxfils J, Eucher C, Elsen M, Cadrobbi J, Tré-Hardy M, Dogné JM, Favresse J. Clinical performance of the Panbio assay for the detection of SARS-CoV-2 IgM and IgG in COVID-19 patients. J Med Virol. 2021 May;93(5):3277-3281.

Thémans P, Dauby N, Schrooyen L, Lebout F, Delforge M, Nasreddine R, Libois A, Payen MC, Konopnicki D, Wuillaume F, Lescrainier C, Verlinden V, Dogné JM, Hamdani J, Musuamba FT. Model informed dosing of hydroxycholoroquine in COVID-19 patients: Learnings from the recent experience, remaining uncertainties and gaps. Br J Clin Pharmacol. 2021 Feb;87(2):674-682.

Bielarz V, Willemart K, Avalosse N, De Swert K, Lotfi R, Lejeune N, Poulain F, Ninanne N, Gilloteaux J, Gillet N, Nicaise C. Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection. Brain Res. 2021 Feb 5:147344.

Favresse J, Gillot C, Oliveira M, Cadrobbi J, Elsen M, Eucher C, Laffineur K, Rosseels C, Van Eeckhoudt S, Nicolas JB, Morimont L, Dogné JM, Douxfils J. Head-to-Head Comparison of Rapid and Automated Antigen Detection Tests for the Diagnosis of SARS-CoV-2 Infection. J Clin Med. 2021 Jan 13;10(2):E265.

Tré-Hardy M, Wilmet A, Beukinga I, Favresse J, Dogné JM, Douxfils J, Blairon L. Analytical and clinical validation of an ELISA for specific SARS-CoV-2 IgG, IgA and IgM antibodies. J Med Virol. 2021 Feb;93(2):803-811.

Hardy M, Michaux I, Lessire S, Douxfils J, Dogné JM, Bareille M, Horlait G, Bulpa P, Chapelle C, Laporte S, Testa S, Jacqmin H, Lecompte T, Dive A, Mullier F. Prothrombotic disturbances of hemostasis of patients with severe COVID-19: A prospective longitudinal observational study. Thromb Res. 2021 Jan;197:20-23.

Blairon L, Piteüs S, Beukinga I, Tré-Hardy M. Development and implementation of a RT-qPCR extraction-free protocol for the detection of SARS-CoV-2 and impact on the turn-around-time. J Med Virol. 2021 Apr;93(4):2538-2542.

Blairon L, Mokrane S, Wilmet A, Dessilly G, Kabamba-Mukadi B, Beukinga I, Tré-Hardy M. Large-scale, molecular and serological SARS-CoV-2 screening of healthcare workers in a 4-site public hospital in Belgium after COVID-19 outbreak. J Infect. 2021 Jan;82(1):159-198.

2020

Favresse J, Elsen M, Eucher C, Laffineur K, Van Eeckhoudt S, Nicolas JB, Gillot C, Dogné JM, Douxfils J. Long-term kinetics of anti-SARS-CoV-2 antibodies in a cohort of 197 hospitalized and non-hospitalized COVID-19 patients. Clin Chem Lab Med. 2020 Dec 18;59(5):e179-e183.

Gillot C, Douxfils J, Cadrobbi J, Laffineur K, Dogné JM, Elsen M, Eucher C, Melchionda S, Modaffarri É, Tré-Hardy M, Favresse J. An Original ELISA-Based Multiplex Method for the Simultaneous Detection of 5 SARS-CoV-2 IgG Antibodies Directed against Different Antigens. J Clin Med. 2020 Nov 21;9(11):E3752.

Hardy M, Michaux I, Lessire S, Douxfils J, Dogné JM, Bareille M, Horlait G, Bulpa P, Chapelle C, Laporte S, Testa S, Jacqmin H, Lecompte T, Dive A, Mullier F. Prothrombotic hemostasis disturbances in patients with severe COVID-19: Individual daily data. Data Brief. 2020 Dec;33:106519.

Vanwambeke SO, Linard C, Gilbert M, Dellicour S. SARS-CoV-2 emergence and diffusion: a new disease manifesting human-environment interactions and a global geography of health. Curr Opin Environ Sustain. 2020 Oct 27.

Barakat T, Muylkens B, Su BL. Is Particulate Matter of Air Pollution a Vector of Covid-19 Pandemic? Matter. 2020 Oct 7;3(4):977-980.

Hardy M, Douxfils J, Dogné JM, Lessire S, Chatelain B, Testa S, Gouin-Thibault I, Gruel Y, Lecompte T, Mullier F. Management of the thrombotic risk associated with COVID-19: what is the role of the hemostasis laboratory? Ann Biol Clin (Paris). 2020 Oct 1;78(5):471-481.

Thémans P, Belkhir L, Dauby N, Yombi JC, De Greef J, Delongie KA, Vandeputte M, Nasreddine R, Wittebole X, Wuillaume F, Lescrainier C, Verlinden V, Kiridis S, Dogné JM, Hamdani J, Wallemacq P, Musuamba FT. Population Pharmacokinetics of Hydroxychloroquine in COVID-19 Patients: Implications for Dose Optimization. Eur J Drug Metab Pharmacokinet. 2020 Dec;45(6):703-713.

Yang J, Petitjean SJL, Koehler M, Zhang Q, Dumitru AC, Chen W, Derclaye S, Vincent SP, Soumillion P, Alsteens D. Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor. Nat Commun. 2020 Sep 11;11(1):4541.

Hardy M, Lecompte T, Douxfils J, Lessire S, Dogné JM, Chatelain B, Testa S, Gouin-Thibault I, Gruel Y, Medcalf RL, Ten Cate H, Lippi G, Mullier F. Management of the thrombotic risk associated with COVID-19: guidance for the hemostasis laboratory. Thromb J. 2020 Sep 7;18:17.

Candellier A, Scohy A, Gillet N, Muylkens B, Morelle J, Belkhir L, Coupeau D, Jadoul M, Goffin É. Absence of SARS-CoV-2 in the effluent of peritoneal dialysis patients. Perit Dial Int. 2020 Sep;40(5):499-503.

Coupeau D, Burton N, Lejeune N, Loret S, Petit A, Pejakovic S, Poulain F, Bonil L, Trozzi G, Wiggers L, Willemart K, André E, Laenen L, Cuypers L, Van Ranst M, Bogaerts P, Muylkens B, Gillet NA. SARS-CoV-2 Detection for Diagnosis Purposes in the Setting of a Molecular Biology Research Lab. Methods Protoc. 2020 Aug 18;3(3):E59.

Mairesse A, Favresse J, Eucher C, Elsen M, Tré-Hardy M, Haventith C, Gruson D, Dogné JM, Douxfils J, Göbbels P. High clinical performance and quantitative assessment of antibody kinetics using a dual recognition assay for the detection of SARS-CoV-2 IgM and IgG antibodies. Clin Biochem. 2020 Aug 25:S0009-9120(20)30817-1.

Hardy M, Douxfils J, Bareille M, Lessire S, Gouin-Thibault I, Fontana P, Lecompte T, Mullier F. Studies on hemostasis in COVID-19 deserve careful reporting of the laboratory methods, their significance and their limitations. J Thromb Haemost. 2020 Nov;18(11):3121-3124.

Thémans P, Dauby N, Schrooyen L, Lebout F, Delforge M, Nasreddine R, Libois A, Payen MC, Konopnicki D, Wuillaume F, Lescrainier C, Verlinden V, Dogné JM, Hamdani J, Musuamba FT. Model informed dosing of hydroxycholoroquine in COVID-19 patients: Learnings from the recent experience, remaining uncertainties and gaps. Br J Clin Pharmacol. 2020 Jun 19.

Favresse J, Eucher C, Elsen M, Laffineur K, Dogné JM, Douxfils J. Response of anti-SARS-CoV-2 total antibodies to nucleocapsid antigen in COVID-19 patients: a longitudinal study. Clin Chem Lab Med. 2020 Sep 25;58(10):e193-e196.

Favresse J, Eucher C, Elsen M, Graux C, Goebels P, Laffineur K, Nicolas JB, Dogné JM, Douxfils J. Unexpected kinetics of anti-SARS-CoV-2 total antibodies in two patients with chronic lymphocytic leukemia. Br J Haematol. 2020 Jun 17.

Favresse J, Eucher C, Elsen M, Tré-Hardy M, Dogné JM, Douxfils J. Clinical performance of the Elecsys electrochemiluminescent immunoassay for the detection of SARS-CoV-2 total antibodies. Clin Chem. 2020 Aug 1;66(8):1104-1106.

Blairon L, Wilmet A, Beukinga I, Tré-Hardy M. Implementation of rapid SARS-CoV-2 antigenic testing in a laboratory without access to molecular methods: Experiences of a general hospital. J Clin Virol. 2020 May 30;129:104472.

Tré-Hardy M, Wilmet A, Beukinga I, Dogné JM, Douxfils J, Blairon L. Validation of a chemiluminescent assay for specific SARS-CoV-2 antibody. Clin Chem Lab Med. 2020 Jul 28;58(8):1357-1364.

Tré-Hardy M, Blairon L, Wilmet A, Beukinga I, Malonne H, Dogné JM, Douxfils J. The role of serology for COVID-19 control: Population, kinetics and test performance do matter. J Infect. 2020 May 15:S0163-4453(20)30297-8.