Diabetes, obesity, kidney & metabolism



Mairesse A, Wauthier L, Courcelles L, Luyten U, Burlacu MC, Maisin D, Favresse J, van Dievoet MA, Gruson D. Biological variation and analytical goals of four thyroid function biomarkers in healthy European volunteers. Clin Endocrinol (Oxf). 2020 Oct 26.

Dogné S, Flamion B. Endothelial glycocalyx impairment in disease: Focus on hyaluronan shedding. Am J Pathol. 2020 Apr;190(4):768-780.


Petrey AC, Obery DR, Kessler SP, Zawerton A, Flamion B, de la Motte CA. Platelet hyaluronidase-2 regulates the early stages of inflammatory disease in colitis. Blood. 2019 Aug 29;134(9):765-775.


Gilloteaux J, Subramanian K, Solomon N, Nicaise C. The leptin receptor mutation of the obese Zucker rat causes sciatic nerve demyelination with a centripetal pattern defect. Ultrastruct Pathol. 2018 Sep-Oct;42(5):377-408.

Dogné S, Flamion B, Caron N. Endothelial Glycocalyx as a Shield Against Diabetic Vascular Complications: Involvement of Hyaluronan and Hyaluronidases. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1427-1439.

Kehoe K, Noels H, Theelen W, De Hert E, Xu S, Verrijken A, Arnould T, Fransen E, Hermans N, Lambeir AM, Venge P, Van Gaal L, De Meester I. Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects. PLoS One. 2018 May 17;13(5):e0197603.

Baudoux T, Husson C, De Prez E, Jadot I, Antoine MH, Nortier JL, Hougardy JM. CD4(+) and CD8(+) T Cells Exert Regulatory Properties During Experimental Acute Aristolochic Acid Nephropathy. Sci Rep. 2018 Mar 28;8(1):5334.

Demine S, Tejerina S, Bihin B, Thiry M, Reddy N, Renard P, Raes M, Jadot M, Arnould T. Mild mitochondrial uncoupling induces HSL/ATGL-independent lipolysis relying on a form of autophagy in 3T3-L1 adipocytes. J Cell Physiol. 2018 Feb;233(2):1247-1265.

Martin B, Caron N, Jadot I, Colombaro V, Federici G, Depommier C, Declèves AÉ. Evaluation of inducible nitric oxide synthase inhibition on kidney function and structure in high-fat diet-induced kidney disease. Exp Physiol. 2018 Jan 1;103(1):125-140.


Jadot I, Colombaro V, Martin B, Habsch I, Botton O, Nortier J, Declèves AE, Caron N. Restored nitric oxide bioavailability reduces the severity of acute-to-chronic transition in a mouse model of aristolochic acid nephropathy. PLoS One. 2017 Aug 23;12(8):e0183604.

Jadot I, Declèves AE, Nortier J, Caron N. An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature. Int J Mol Sci. 2017 Jan 29;18(2).


Dogné S, Rath G, Jouret F, Caron N, Dessy C, Flamion B. Hyaluronidase 1 deficiency preserves endothelial function and glycocalyx integrity in early streptozotocin-induced diabetes. Diabetes. 2016 Sep;65(9):2742-53.

Bourguignon V, Flamion B. Respective roles of hyaluronidases 1 and 2 in endogenous hyaluronan turnover. FASEB J. 2016 Jun;30(6):2108-14.

Declèves AÉ, Jadot I, Colombaro V, Martin B, Voisin V, Nortier J, Caron N. Protective effect of nitric oxide in aristolochic acid-induced toxic acute kidney injury: an old friend with new assets. Exp Physiol. 2016 Jan;101(1):193-206.

VIEWPOINT: Gewin L. NO clue to pathogenesis of aristolochic acid nephropathy. Exp Physiol. 2016 Jan;101(1):33. Comment on Exp Physiol. 2016 Jan;101(1):193-206. Protective effect of nitric oxide in aristolochic acid-induced toxic acute kidney injury: an old friend with new assets.

Malaisse J, Pendaries V, Hontoir F, De Glas V, Van Vlaender D, Simon M, Lambert de Rouvroit C, Poumay Y, Flamion B. Hyaluronan does not regulate human epidermal keratinocyte proliferation and differentiation. J Biol Chem. 2016 Mar 18;291(12):6347-58.

Petrey AC, Obery DR, Kessler SP, Flamion B, de la Motte CA. Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis. Am J Pathol. 2016 Sep;186(9):2390-403.


Colombaro V, Jadot I, Declèves AE, Voisin V, Giordano L, Habsch I, Malaisse J, Flamion B, Caron N. Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis. Kidney Int. 2015 Jul;88(1):61-71.

Colombaro V, Jadot I, Declèves AE, Voisin V, Giordano L, Habsch I, Flamion B, Caron N. Hyaluronidase 1 and hyaluronidase 2 are required for renal hyaluronan turnover. Acta Histochem. 2015 Jan;117(1):83-91.


Voisin V, Decleves A, Hubert V, Colombaro V, Giordano L, Habsch I, Bouby N, Nonclercq D, Caron N Protection of Wistar-Furth rats from post-ischemic acute renal injury: a role for Nitric Oxide and Thromboxane? Clinical and experimental pharmacology & physiology 2014 Nov;41(11):911-20.


Hulsmans M, Geeraert B, Arnould T, Tsatsanis C, Holvoet P PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression PloS one 2013, 8:e62253.

Colombaro V, Decleves AE, Jadot I, Voisin V, Giordano L, Habsch I, Nonclercq D, Flamion B, Caron N Inhibition of hyaluronan is protective against renal ischaemia-reperfusion injury. Nephrol Dial Transplant 2013, 28:2484-2493.

Decleves, A. , Pozdzik, A. , Baudoux, T. , Habsch, I. , De Prez, E. , Flamion, B. , Nortier, J. , Caron, N. CD44-positive cells and hyaluronan are a hallmark of a rat model of aristolochic acid nephropathy. J Cytol Histol 2013, 4: 186


Demine S, Michel S, Vannuvel K, Wanet A, Renard P, Arnould T Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins (Review). Cells 2012, 1(2):168-203.

De Pauw A, Demine S, Tejerina S, Dieu M, Delaive E, Kel A, Renard P, Raes M, Arnould T Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction American journal of physiology Endocrinology and metabolism 2012, 302:E1123-1141.