Program

08:45    Registration & Welcome coffee

09:30    Introduction to the Conference by Prof. Patsy Renard, UNamur

09:35    Organization of RNA in space and time

Prof. Nikolaus RAJEWSKY, Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin (Germany)

10:05    Roles and regulation of non-coding RNAs in viral infections

Dr. Sébastien PFEFFER, Architecture and Reactivity of RNA, Institut de Biologie Moléculaire et Cellulaire du CNRS, Université de Strasbourg (France)    

10:35    Understanding flavivirus pathogenesis: three-hybrid screening for host factors hijacked by viral non-coding RNA

Sander JANSEN, Laboratory of Virology and Chemotherapy, Rega Institute, KU Leuven (Belgium)

10:50   Coffee break

11:20    A non-coding compendium of brain development identifies B13, a novel long non-coding RNA with cell intrinsic and cell extrinsic roles in neuronal progenitor cell fate          

Dr. Julieta APREA PEREZ, Center for Regenerative Therapies, School of Medicine, Technische Universität Dresden (Germany)

11:50    Exposure to ionizing radiation triggers prolonged changes in circular RNA abundance in the embryonic mouse brain and primary neurons

Auchi INALEGWU, Radiobiology Unit, Belgian Nuclear Research Centre, SCK·CEN (Belgium)

12:05    Accurate quantification of endogenous circular RNAs using NanoString technology SPONSORED TALK

Dr. Lasse KRISTENSEN, Department of Molecular Biology and Genetics, Aarhus University (Denmark)

12:20    New Bio-Rad long non-coding RNA qPCR workflow SPONSORED TALK 

Dr. Caroline WEYDERT, Bio-Rad (Belgium)

12:35   Lunch & poster session

13:50    LncRNAs and beyond: uncoupling cytosolic and mitochondrial-translation as an effective anti-melanoma strategy           

Prof. Eleonora LEUCCI, Laboratory for RNA Cancer Biology, Department of Oncology, KU Leuven (Belgium)

14:20    TRMT10A deficiency and tRNA fragmentation lead to mitochondrial dysfunction and β-cell demise in rare and common forms of diabetes

Maria Nicol ARROYO, ULB Center for Diabetes Research, ULB (Belgium)

14:35    Codon-specific translation regulation through tRNA modification in cancer

Dr. Pierre CLOSE, Laboratory of Cancer Signaling, GIGA-Stem Cells, ULiège (Belgium)

15:05    Coffee break

15:35    Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome

Dr. Maxime WERY, ncRNA, epigenetic and genome fluidity, Institut Curie, Sorbonne Université, Paris (France)

15:50    Expression of small nucleolar RNAs (D32A, D33, D35) associated with ageing and osteoarthritis in man and horses

Dr. Fanny HONTOIR, Integrated Veterinary Research Unit, NARILIS, UNamur (Belgium)

16:05    Unravelling the exosomal export of miR-503, a key modulator in resistance to chemotherapy in breast cancer cells

Amandine BOECKX, Molecular Angiogenesis Laboratory, GIGA-Cancer, ULiège (Belgium)

16:20    Non-coding RNAs as biomarkers & therapeutic targets

Prof. Pieter MESTDAGH, Bioinformatics and Functional Genomics Lab, Cancer Research Institute Ghent, Center for Medical Genetics, UGent (Belgium)

16:50    Concluding remarks and Awards by Prof. Charles Nicaise, UNamur

17:00    Drink