Non-coding RNA in health and disease

 

Join us at the BSCDB-NARILIS Joint Meeting 2020

Protein-coding genes account for less than 2% of the entire genome. The other 98% were considered for years as “junk” DNA as they correspond to non-coding genomic sequences. However, it is now becoming clear that the major part of the genome is transcribed into RNA molecules and that these non-coding RNAs have important regulatory roles in gene expression.

Small non-coding RNAs, long non-coding RNAs and circular RNAs

The present meeting will focus on this non-coding part of the genome, which still remains largely unexplored. It will shed light on recent advances in the discovery of new non-coding RNAs and their functional characterization. The topics covered during the meeting will relate both to small non-coding RNAs (i.e. miRNA), as well as to the more recently described long non-coding RNAs and circular RNAs. In addition to their involvement in fundamental biological processes, their contribution in various diseases will also be addressed. Their use as diagnostic markers and their potential as future therapeutic targets will be discussed.

Discover the speakers

 

 Dr. Julieta APREA PEREZ

Center for Regenerative Therapies, School of Medicine, Technische Universität Dresden

Dr. Pierre CLOSE

Laboratory of Cancer Signaling, GIGA-Stem Cells, ULiège

 

Prof. Eleonora LEUCCI

Laboratory for RNA Cancer Biology, Department of Oncology, KU Leuven

 
     

Prof. Pieter MESTDAGH

Bioinformatics and Functional Genomics Lab, Cancer Research Institute Ghent, Center for Medical Genetics, Ghent University

Dr. Sébastien PFEFFER

Architecture and Reactivity of RNA, Institut de Biologie Moléculaire et Cellulaire du CNRS, Université de Strasbourg

Prof. Nikolaus RAJEWSKY

Laboratory for Systems Biology of Gene Regulatory Elements, Max Delbrück Center for Molecular Medicine, Berlin