Anne-Laure Sennesael

Clinical pharmacy

Dr. Anne-Laure Sennesael PharmD, PhD

CHU UCL Namur, Site Godinne, Pharmacy department

Member of the Namur Thrombosis & Hemostasis Center (NTHC)

ORCID | ResearchGate | LinkedIn

Expertise and research interests

Anne-Laure Sennesael holds a PhD thesis in Pharmaceutical Sciences from the UCLouvain. She is clinical pharmacist at the CHU UCL Namur since November 2018. Her research interests focus on anticoagulation management.

Research projects

Exploring adverse drug reactions associated with the use of direct oral anticoagulants : from greater fundamental knowledge to better clinical prevention. PhD thesis defended by Anne-Laure Sennesael on 13/09/2018. Under co-supervision by Prof. Anne Spinewine, UCLouvain, LDRI and Prof. Jean-Michel Dogné, UNamur, NARILIS.

Selected publications

Sennesael AL, Larock AS, Hainaut P, Lessire S, Hardy M, Douxfils J, Spinewine A, Mullier F. The impact of strong inducers on direct oral anticoagulant levels. Am J Med. 2021 Oct;134(10):1295-1299.

Sennesael AL, Krug B, Sneyers B, Spinewine A. Do computerized clinical decision support systems improve the prescribing of oral anticoagulants? A systematic review. Thromb Res. 2020 Mar;187:79-87.

Sennesael AL, Larock AS, Douxfils J, Elens L, Stillemans G, Wiesen M, Taubert M, Dogné JM, Spinewine A, Mullier F. Rivaroxaban plasma levels in patients admitted for bleeding events: insights from a prospective study. Thromb J. 2018 Nov 12;16:28.

Sennesael AL, Panin N, Vancraeynest C, Pochet L, Spinewine A, Haufroid V, Elens L. Effect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines. Sci Rep. 2018 Jul 12;8(1):10514.

Sennesael AL, Dalleur O, Henrard S, Artoisenet C, Schoevaerdts D, Spinewine A. Implementing a screening tool to improve prescribing in hospitalized older patients: a pilot study. Int J Clin Pharm. 2018 Feb;40(1):15-19.

Sennesael AL, Larock AS, Devalet B, Mathieux V, Verschuren F, Muschart X, Dalleur O, Dogné JM, Spinewine A. Preventability of serious thromboembolic and bleeding events related to the use of oral anticoagulants: a prospective study. Br J Clin Pharmacol. 2018 Jul;84(7):1544-1556.

Sennesael AL, Exner T, Chatelain B, Lessire S, Larock AS, Vancraeynest C, Pochet L, Dogné JM, Spinewine A, Mullier F, Douxfils J. An optimized dRVVT-based  assay to estimate the intensity of anticoagulation in patients treated with direct oral anticoagulants. Thromb Res. 2017 Jun 28;157:29-37.

Sennesael AL, Dogné JM, Spinewine A. Optimizing the Safe Use of Direct Oral Anticoagulants in Older Patients: A Teachable Moment. (2015) JAMA Internal Medicine, 175 (10), pp. 1608-1609.