NAmur Research Institute for LIfe Sciences
Benoît Rondelet
Brain death-induced lung injury and heart dysfunction
Prof. Benoît Rondelet MD, PhD
CHU UCL Namur, Site Godinne, Department of Cardio-Vascular, Thoracic Surgery and Lung Transplantation
Group medical director of CHU UCL Namur (Dinant, Godinne and Sainte-Elisabeth)
Member of Institute of Experimental and Clinical Research (IREC), UCLouvain
Expertise and research interests
Lung Diseases - Pulmonary Hypertension - Pulmonary Circulation - Lung Compliance
Cardiomyopathies - Heart Failure - Heart Transplantation
Research projects
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In collaboration with UNamur |
- Controlled growth factor delivery for therapeutic angiogenesis into the heart by cell-based gene expression or fibrin-based protein release. PhD thesis defended by Dr. Ludovic Melly on 02/07/2020. Under the supervision of Prof. Benoît Rondelet, CHU UCL Namur.
- Determinant of brain death-induced lung injury. Research project by . Supported by the Fondation Mont-Godinne.
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Rôles de l’inflammation et de l’apoptose dans la perturbation du dialogue cœur-poumon : applications particulières à la mort cérébrale. PhD thesis defended by Dr. Asmae Belhaj on 07/06/2016. Under co-supervision by Prof. Benoît Rondelet, CHU UCL Namur; Prof. Kathleen Mc Entee, ULB; Prof. Robert Naeije, ULB.
Selected publications
Rondelet B, Dehanne F, Van Den Bulcke J, Martins D, Belhaj A, Libert B, Leclercq P, Pirson M. Daly/Cost comparison in the management of peripheral arterial disease at 17 Belgian hospitals. BMC Health Serv Res. 2024 Jan 19;24(1):109.
Kuzmova M, Rondelet B, Belhaj A. A rare case of aortic endograft infection by Francisella tularensis: A case report. Int J Surg Case Rep. 2023 Aug 18;110:108685.
Belhaj A, Dewachter L, Monier A, Vegh G, Rorive S, Remmelink M, Closset M, Melot C, Creteur J, Salmon I, Rondelet B. Beneficial Effects of Tacrolimus on Brain-Death-Associated Right Ventricular Dysfunction in Pigs. Int J Mol Sci. 2023 Jun 21;24(13):10439.
Belhaj A, Dewachter L, Hupkens E, Remmelink M, Galanti L, Rorive S, Melot C, Naeije R, Rondelet B. Tacrolimus Prevents Mechanical and Humoral Alterations in Brain Death-induced Lung Injury in Pigs. Am J Respir Crit Care Med. 2022 Sep 1;206(5):584-595.
Melly L, Grosso A, Stanciu Pop C, Yu-Hsuan C, Nollevaux MC, Schachtrup C, Marsano A, Di Maggio N, Rondelet B, Banfi A. Fibrin hydrogels promote scar formation and prevent therapeutic angiogenesis in the heart. J Tissue Eng Regen Med. 2020 Oct;14(10):1513-1523.
Melly L, Cerino G, Frobert A, Cook S, Giraud MN, Carrel T, Tevaearai Stahel HT, Eckstein F, Rondelet B, Marsano A, Banfi A. Myocardial infarction stabilization by cell-based expression of controlled Vascular Endothelial Growth Factor levels. J Cell Mol Med. 2018 May;22(5):2580-2591.
Belhaj A, Dewachter L, Rorive S, Remmelink M, Weynand B, Melot C, Hupkens E, Dewachter C, Creteur J, Mc Entee K, Naeije R, Rondelet B. Mechanical versus humoral determinants of brain death-induced lung injury. PLoS One. 2017 Jul 28;12(7):e0181899.
Belhaj A, Boven C, Dewachter L, Ruiz Patino M, Sokolow Y, Rondelet B. Influence of Donor Lung Surfactant-A and -B Protein Expression on the Development of Primary Graft Dysfunction After Lung Transplantation: A Pilot Study. Ann Transplant. 2017 Jun 16;22:361-369.
Belhaj A, Dewachter L, Rorive S, Remmelink M, Weynand B, Melot C, Galanti L, Hupkens E, Sprockeels T, Dewachter C, Creteur J, McEntee K, Naeije R, Rondelet B. Roles of inflammation and apoptosis in experimental brain death-induced right ventricular failure. J Heart Lung Transplant. 2016 Dec;35(12):1505-1518.
Belhaj A, Dewachter L, Kerbaul F, Brimioulle S, Dewachter C, Naeije R, Rondelet B. Heme oxygenase-1 and inflammation in experimental right ventricular failure on prolonged overcirculation-induced pulmonary hypertension. PLoS One. 2013 Jul 25;8(7):e69470.
