François-Xavier Sibille

Deprescribing in geriatric medicine

Dr François-Xavier SibilleDr. François-Xavier Sibille MD

CHU UCL Namur, Site Godinne, Department of geriatrics

Member of Institute of Health and Society (IRSS), UCLouvain

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Expertise and research interests

Deprescription, barriers, facilitators, benzodiazepine receptor agonists, nursing homes, patients’ attitudes, older patients, end-of-life care

Research project

  • ONGOING Deprescribing benzodiazepine receptor agonists in hospitalized older patients: opportunities and challenges (DeBeHOP). Ongoing PhD thesis by Dr. François-Xavier Sibille, UCLouvain, IRSS. Under co-supervision by Prof. Marie de Saint-Hubert, CHU UCL Namur (promoter) and Prof. Anne Spinewine, UCLouvain, LDRI (co-promoter).

Selected publications

Sibille FX, de Saint-Hubert M, Henrard S, Aubert CE, Goto NA, Jennings E, Dalleur O, Rodondi N, Knol W, O'Mahony D, Schwenkglenks M, Spinewine A. Benzodiazepine Receptor Agonists Use and Cessation Among Multimorbid Older Adults with Polypharmacy: Secondary Analysis from the OPERAM Trial. Drugs Aging. 2023 Jun;40(6):551-561.

Sibille FX, Spinewine A, Zerah L, Maljean L, Schoevaerdts D, de Saint-Hubert M. Current practice in benzodiazepine receptor agonists deprescribing on acute geriatric wards: a cohort study. BMC Geriatr. 2022 Feb 1;22(1):88.

Roux B, Rakheja B, Sirois C, Niquille A, Pétein C, Ouellet N, Spinewine A, Sibille FX, Laroche ML. Attitudes and beliefs of older adults and caregivers towards deprescribing in French-speaking countries: a multicenter cross-sectional study. Eur J Clin Pharmacol. 2022 Oct;78(10):1633-1646.

Sallevelt BTGM, Egberts TCG, Huibers CJA, Ietswaart J, Drenth-van Maanen AC, Jennings E, O'Mahony C, Jungo KT, Feller M, Rodondi N, Sibille FX, Spinewine A, van Puijenbroek EP, Wilting I, Knol W. Detectability of Medication Errors With a STOPP/START-Based Medication Review in Older People Prior to a Potentially Preventable Drug-Related Hospital Admission. Drug Saf. 2022 Dec;45(12):1501-1516.

Schoevaerdts D, Sibille FX, Gavazzi G. Infections in the older population: what do we know? Aging Clin Exp Res. 2021 Mar;33(3):689-701.

Roux B, Sirois C, Niquille A, Spinewine A, Ouellet N, Pétein C, Sibille FX, Csajka C, Reeve E, Villeneuve C, Laroche ML. Cross-cultural adaptation and psychometric validation of the revised Patients' Attitudes Towards Deprescribing (rPATD) questionnaire in French. Res Social Adm Pharm. 2021 Aug;17(8):1453-1462.

Sibille FX, Pétein C, Evrard P, Mouzon A, Thevelin S, de Saint-Hubert M, Spinewine A. La déprescription chez la personne âgée. In: Louvain médical, Vol. 139, no. 02, p. 71-77 (2020)