Jonathan Degosserie

Namur Molecular Tech

Dr. Jonathan Degosserie PhD

CHU UCL Namur, Site Godinne, Department of Laboratory Medicine

Co-head of Molecular Biology

Head of the Namur Molecular Tech (NMT)

ORCID | Linkedin

Expertise and research interests

Jonathan Degosserie holds a PhD in Biomedical and pharmaceutical sciences from the UCLouvain. He carried out his doctoral research at de Duve Institute in the laboratory of Prof. Christophe Pierreux. His PhD thesis focused on the role of extracellular vesicles as communication vehicles during thyroid organogenesis and establishment of thyroid cancer. Read thesis summary

After 2 years working as a consultant in the R&D department of GSK Vaccines, Jonathan joined the CHU UCL Namur as supervising scientist and coordinator of the COVID-19 testing platform. Together with his team, they developed a broad experience in NGS, working routinely with short- and long-read technologies. In January 2023 he launched a molecular biology technology platform dedicated to research, at the CHU UCL Namur. Read more about Namur Molecular Tech

Jonathan developed and expertise in cellular and molecular biology. His main research interest lies in the field of oncology and the genetic mechanisms underlying development and progression of tumors. Jonathan’s research focuses on the genetic biomarkers found in liquid biopsies and their role as diagnostic and prognostic tools.

Team

  • Léonore Bleret, Research Assistant
  • Nicolas Debortoli, Post-Doc (Bioinformatician)
  • Louise Janssens, Medical Laboratory Technician
  • Céline Maschietto, PhD. Candidate
  • Lesly Nyinkeu, Medical Laboratory Technician
  • Gaetan Otto, Quality Manager
  • Edith Renguet, Post-Doc

Research project

Deciphering the potential of liquid biopsies and extracellular vesicles for the follow-up of patients with non-small cell lung carcinoma.

Selected publications

Soleimani R, Cabo J, Frelik A, Debry C, Mbende C, Delcourt J, Debortoli N, Renguet E, Devey A, Mullier F, Degosserie J, Moreno Y Banuls L. SLC14A1 gene sequencing shows the JK*01W.06 allele in a JK1 patient with an anti-JK1. Hematol Transfus Cell Ther. 2023 Dec 17:S2531-1379(23)02591-9.

Maschietto C, Otto G, Rouzé P, Debortoli N, Bihin B, Nyinkeu L, Denis O, Huang TD, Mullier F, Bogaerts P, Degosserie J. Minimal requirements for ISO15189 validation and accreditation of three next generation sequencing procedures for SARS-CoV-2 surveillance in clinical setting. Sci Rep. 2023 Apr 28;13(1):6934.

Bayart JL, Degosserie J, Favresse J, Gillot C, Didembourg M, Djokoto HP, Verbelen V, Roussel G, Maschietto C, Mullier F, Dogné JM, Douxfils J. Analytical Sensitivity of Six SARS-CoV-2 Rapid Antigen Tests for Omicron versus Delta Variant. Viruses. 2022 Mar 22;14(4):654.

Delcorte O, Degosserie J, Pierreux CE. Role of Extracellular Vesicles in Thyroid Physiology and Diseases: Implications for Diagnosis and Treatment. Biomedicines. 2022 Oct 15;10(10):2585.

Delcorte O, Spourquet C, Lemoine P, Degosserie J, Van Der Smissen P, Dauguet N, Loriot A, Knauf JA, Gatto L, Marbaix E, Fagin JA, Pierreux CE. BRAFV600E Induction in Thyrocytes Triggers Important Changes in the miRNAs Content and the Populations of Extracellular Vesicles Released in Thyroid Tumor Microenvironment. Biomedicines. 2022 Mar 23;10(4):755.

Degosserie J, Heymans C, Spourquet C, Halbout M, D'Auria L, Van Der Smissen P, Vertommen D, Courtoy PJ, Tyteca D, Pierreux CE. Extracellular vesicles from endothelial progenitor cells promote thyroid follicle formation. J Extracell Vesicles. 2018 Jun 28;7(1):1487250.

Contact

jonathan.degosserie@chuuclnamur.uclouvain.be