Pierre Bogaerts

Molecular clinical microbiology

Prof. Pierre Bogaerts Ir, PhD

CHU UCL Namur, Site Godinne, Department of Clinical Microbiology

Head of the National Reference Center for Antibiotic-Resistant Gram-Negative Bacilli

Head of the National Reference Center for Helicobacter pylori

Member of Institute of Experimental and Clinical Research (IREC), UCLouvain

Member of the Namur Research Pole in Infectiology (NaRePI)

ORCID | ResearchGate | LinkedIn

Expertise and research interests

Evaluation and development of in vitro diagnostic tools for the detection of antibiotic resistance markers in Gram-negatives and in H. pylori

Surveillance of antimicrobial resistance, phenotypic and molecular characterization of the resistance mechanisms  in Gram-negatives and in H. pylori

Exploration of new antibacterial drugs or strategies to overcome pandrug-resistant bacteria

Team member

PhD student: Pauline Rouzé, UCLouvain

Research projects

  • ONGOING Application of Targeted-Antibacterial-Plasmids against Antimicrobial Resistant Strains. Ongoing PhD thesis by Pauline Rouzé, UCLouvain. Under co-supervision by Prof. Te-Din Huang (promoter) and Prof. Pierre Bogaerts (co-promoter), CHU UCL Namur.  
  • Comparaison de 2 tests immunochromatographiques commerciaux pour l’identification de carbapénémases d’entérobactéries. Mémoire réalisé par Anne-Sophie Berger, HELHA. Sous la supervision du Prof. Pierre Bogaerts, CHU UCL Namur (2018).

   In collaboration with UNamur

  • The prevalence and the resistance mechanisms of colistin-resistant E. coli (COLREC) at the human-livestock interface in an One Health approach. Research collaboration between Prof. Benoît Muylkens, UNamur; Prof. Te-Din Huang, Prof. Pierre Bogaerts and Prof. Youri Glupczynski, CHU UCL Namur; Dr. Marc Saulmont, Arsia; Prof. Catherine Linard, UNamur (2018).
  • Improvement of identification of Capnocytophaga canimorsus by matrix-assisted laser desorption ionization-time of flight mass spectrometry using enriched database. Research collaboration between Prof. Francesco Renzi and Prof. Guy Cornelis, UNamur; Prof. Te-Din Huang, Prof. Pierre Bogaerts and Prof. Youri Glupczynski, CHU UCL Namur (2015).

Selected publications

Maschietto C, Otto G, Rouzé P, Debortoli N, Bihin B, Nyinkeu L, Denis O, Huang TD, Mullier F, Bogaerts P, Degosserie J. Minimal requirements for ISO15189 validation and accreditation of three next generation sequencing procedures for SARS-CoV-2 surveillance in clinical setting. Sci Rep. 2023 Apr 28;13(1):6934.

de Barsy M, Mercuri PS, Oueslati S, Elisée E, Huang TD, Sacré P, Iorga BI, Naas T, Galleni M, Bogaerts P. Detection and Characterization of VIM-52, a New Variant of VIM-1 from a Klebsiella pneumoniae Clinical Isolate. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0266020.

Bogaerts P, Berger AS, Evrard S, Huang TD. Comparison of two multiplex immunochromatographic assays for the rapid detection of major carbapenemases in Enterobacterales. J Antimicrob Chemother. 2020 Jun 1;75(6):1491-1494.

Glupczynski Y, Evrard S, Huang TD, Bogaerts P. Evaluation of the RESIST-4 K-SeT assay, a multiplex immunochromatographic assay for the rapid detection of OXA-48-like, KPC, VIM and NDM carbapenemases. J Antimicrob Chemother. 2019 May 1;74(5):1284-1287.

Bogaerts P, Naas T, Saegeman V, Bonnin RA, Schuermans A, Evrard S, Bouchahrouf W, Jove T, Tande D, de Bolle X, Huang TD, Dortet L, Glupczynski Y. OXA-427, a new plasmid-borne carbapenem-hydrolysing class D β-lactamase in Enterobacteriaceae. J Antimicrob Chemother. 2017 Sep 1;72(9):2469-2477.

Bogaerts P, Oueslati S, Meunier D, Nonhoff C, Yunus S, Massart M, Denis O, Woodford N, Hopkins KL, Naas T, Dortet L, Huang TD, Glupczynski Y. Multicentre evaluation of the BYG Carba v2.0 test, a simplified electrochemical assay for the rapid laboratory detection of carbapenemase-producing Enterobacteriaceae. Sci Rep. 2017 Aug 30;7(1):9937.

Bogaerts P, Yunus S, Massart M, Huang TD, Glupczynski Y. Evaluation of the BYG Carba Test, a New Electrochemical Assay for Rapid Laboratory Detection of Carbapenemase-Producing Enterobacteriaceae. J Clin Microbiol. 2016 Feb;54(2):349-58.

Bogaerts P, Cuzon G, Evrard S, Hoebeke M, Naas T, Glupczynski Y. Evaluation of a DNA microarray for rapid detection of the most prevalent extended-spectrum β-lactamases, plasmid-mediated cephalosporinases and carbapenemases in Enterobacteriaceae, Pseudomonas and Acinetobacter. Int J Antimicrob Agents. 2016 Aug;48(2):189-93.

Glupczynski Y, Evrard S, Ote I, Mertens P, Huang TD, Leclipteux T, Bogaerts P. Evaluation of two new commercial immunochromatographic assays for the rapid detection of OXA-48 and KPC carbapenemases from cultured bacteria. J Antimicrob Chemother. 2016 May;71(5):1217-22.

Contact

pierre.bogaerts@chuuclnamur.uclouvain.be