Sarah Lessire

Patient blood management

Prof. Sarah Lessire MD, PhD

CHU UCL Namur, Site Godinne Department of Anesthesiology

Member of the Institute of Experimental and Clinical Research (IREC), UCLouvain

Member of the Namur Thrombosis & Hemostasis Center (NTHC)

ORCID | ResearchGate

Expertise and research interests

Perioperative management of direct oral anticoagulants

Referent anesthesiologist for "Patient Blood Management" at CHU UCL Namur

Coordinator responsible for the implementation of an "Anemia clinic" at CHU UCL Namur

Team members

Clinical Research Associate: Dr. Chloé Nobis

Research projects

  • ONGOING Study of the mechanisms of catheter-associated thrombosis and its pharmacological mitigation using thrombin generation assay in the presence of platelets. Ongoing PhD thesis by Dr. Michaël Hardy. Under co-supervision by Prof. François Mullier, CHU UCL Namur (promoter) and Prof. Sarah Lessire, CHU UCL Namur (co-promoter).

Selected publications

Hardy M, Douxfils J, Dincq AS, Sennesael AL, Xhaet O, Mullier F, Lessire S. Uninterrupted DOACs Approach for Catheter Ablation of Atrial Fibrillation: Do DOACs Levels Matter? Front Cardiovasc Med. 2022 Mar 29;9:864899.

Lessire S, Dincq AS, Siriez R, Pochet L, Sennesael AL, Vornicu O, Hardy M, Deceuninck O, Douxfils J, Mullier F. Assessment of low plasma concentrations of apixaban in the periprocedural setting. Int J Lab Hematol. 2020 Aug;42(4):394-402.

Hardy M, Dupuis C, Dincq AS, Jacqmin H, Lecompte T, Mullier F, Lessire S. Reduction of Preoperative Waiting Time before Urgent Surgery for Patients on P2Y(12) Inhibitors Using Multiple Electrode Aggregometry: A Retrospective Study. J Clin Med. 2020 Feb 4;9(2).

Lessire S, Douxfils J, Pochet L, Dincq AS, Larock AS, Gourdin M, Dogné JM, Chatelain B, Mullier F. Estimation of Rivaroxaban Plasma Concentrations in the Perioperative Setting in Patients With or Without Heparin Bridging. Clin Appl Thromb Hemost. 2018 Jan;24(1):129-138.

Vornicu O, Larock AS, Dincq AS, Douxfils J, Dogné JM, Mullier F, Lessire S. Idarucizumab for the treatment of hemorrhage and dabigatran reversal in patients requiring urgent surgery or procedures. Expert Opin Biol Ther. 2017 Oct;17(10):1275-1296.

Dubois V, Dincq AS, Douxfils J, Ickx B, Samama CM, Dogné JM, Gourdin M, Chatelain B, Mullier F, Lessire S. Perioperative management of patients on direct oral anticoagulants. Thromb J. 2017 May 15;15:14.

Contact

sarah.lessire@chuuclnamur.uclouvain.be