Namur Nanosafety Centre (NNC)
Expertise
Physico-chemical characterization
- Size and morphology: Electron microscopy, Differential centrifuge sedimentation, X-ray diffraction, Surface area
- Chemical composition (bulk and surface): Energy dispersive X-ray (EDX), X-ray photoelectron spectroscopy (XPS)
Multielemental determination in complex matrices (solid and liquid)
- Particle induced X-ray emission (PIXE)
In vivo animal testing
- Oral administration; whole-body airborne nanoaerosol exposure
- Clinical data: plasmatic, urine and feces analysis; biochemistry; hematology; histopathology
- Tissue distribution; biopersistance
Ex vivo human and animal testing
- Hemocompatibility: impact on red blood cells (hemolysis), platelet function and coagulation
In vitro testing
- Cell culture platform for in vitro studies
- Tissue engineering (skin, intestine and lung exposure models) and signalling studies
- Adaptation of testing methods for nanomaterial and nanoparticle safety assessment
Toxicogenomics & Toxicoproteomics
- Microfluidic Real Time RT-PCR
- Gel and gel free proteomics
European projects
QualityNano
A pan-European Infrastructure Project (27 partners) for processing, analysis and characterisation (physico-chemical properties, health and environmental impact) of engineered nanomaterials, nanoparticles and nanostructures. QualityNano will also pro-actively seek to drive, develop and promote the highest quality research and practices via Joint Research Activities, Networking Activities and provision of Transnational Access functions.
NanoValid
Large scale integrated project (29 partners): development of reference methods for hazard indentification, risk assessment and life cycle assessment of engineered nanomaterials
NANoREG
Large scale integrated project: A common European approach to the regulatory testing of Manufactured Nanomaterials.
Establish close cooperation between regulators, industries and scientists.
The innovative and economic potential of Manufacture Nanomaterials (MNMs) is threatened by limited understanding safety along the value chains : today 's knowledge is not comprehensive enough for regulatory purposes. The approach of NANoREG will provide answers to Society, Industry and the National Regulation and Legislation Authorities.
NANOGECO
SIINN-ERA-NET- European Coordinator: Dr Julie LALOY (UNamur)
Integration of nanomaterials in paints
Partners: TU Graz, Fraunhofer IPA
NanoToxClass
SIINN-ERA-NET- European Coordinator: Dr. Andrea Haase (BfR)
Establishing nanomaterial grouping/ classification strategies according to toxicity and biological effects for supporting risk assessment (April 2015- March 2018)
Partners: BfR, UFZ, RKI, BASF, IUTA, UKE, TAU, UNamur, Straticell, ISPUP, UB
Members
DOGNE Jean-Michel | Laboratory investigations in hemostasis
HEUSKIN Anne-Catherine | Radiobiology and radiation therapy research
LUCAS Stéphane | Radiobiology and radiation therapy research