NARILIS lunch seminar | Dr. Gilles Rademaker, ULiège, GIGA Institute

We are pleased to invite you to a seminar given by

Dr. Gilles Rademaker

Postdoctoral researcher at ULiège, GIGA Institute

His seminar is entitled

"Identifying metabolic dependencies in primary versus metastatic pancreatic cancer"

Bio

Gilles Rademaker is a cancer biologist whose research bridges metabolism, cell biology, and the mechanisms that drive metastasis. He studied pharmaceutical sciences at the Université de Liège, where his early work centered on the development of analytical tools for steroid hormone detection using HPLC–MS/MS. He then pursued his PhD at the GIGA Institute in Liège under the supervision of Professors Olivier Peulen and Vincenzo Castronovo, where he investigated the role of myoferlin in digestive cancers.

Following his doctoral training, he moved to the United States to complete a postdoctoral fellowship in the Department of Anatomy at the University of California, San Francisco. There, his research focused on pancreatic ductal adenocarcinoma (PDAC), one of the most aggressive and lethal human cancers. He explored how cancer cells adapt their metabolism to distinct organ environments and how these adaptations dictate metastatic spread. He has authored and co-authored in leading journals including Nature, Science, and Nature Cell Biology, with notable contributions such as uncovering the role of PCSK9 in driving sterol-dependent metastatic organotropism in pancreatic cancer.

Gilles has recently returned to Belgium as a Chargé de recherche with the FNRS at the GIGA Institute in Liège. His current research aims to identify the genetic determinants of metastatic organotropism in digestive cancers and to develop therapeutic strategies tailored to the metastatic site.

Invited by Prof. Marc Hennequart, UNamur, URPhyM