NAmur Research Institute for LIfe Sciences
Nathalie Kirschvink
Vascular physiology
Prof. Nathalie Kirschvink DVM, PhD
UNamur, Department of medicine, Molecular Physiology Research Unit (URPhyM)
Research portal UNamur | ORCID | ResearchGate | LinkedIn
Expertise and research interests
The team of Prof. Nathalie Kirschvink is focusing on the vascular endothelial glycocalyx, as well as on the vascular muscle tone. Their investigations include:
- Characterisation of the glycocalyx function
- Visualisation of the glycocalyx integrity/damage
- Ex vivo vascular tone investigated by pressure myography
Group members
Scientific collaborator: Dr. Sophie Dogné
Senior advisor: Prof. Bruno Flamion
PhD students: Kaoutar Idouz and Benjamin Hanotieau
Technical staff: Sophie Ligot and Jean-François Gaussin
Research projects
ONGOING Impact of brain-death and tacrolimus pretreatment on kidney function in a pig model. Ongoing PhD thesis by Kaoutar Idouz.
ONGOING Ex vivo vascular tone investigated by pressure myography. Ongoing PhD thesis by Benjamin Hanotieau.
Selected publications
Idouz K, Belhaj A, Rondelet B, Dewachter L, Flamion B, Kirschvink N, Dogné S. Cascading renal injury after brain death: Unveiling glycocalyx alteration and the potential protective role of tacrolimus. Front Cell Dev Biol. 2024 Aug 6;12:1449209.
Dogné S, Flamion B. Endothelial glycocalyx impairment in disease: Focus on hyaluronan shedding. Am J Pathol. 2020 Apr;190(4):768-780.
Dogné S, Flamion B, Caron N. Endothelial Glycocalyx as a Shield Against Diabetic Vascular Complications: Involvement of Hyaluronan and Hyaluronidases. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1427-1439.
