NAmur Research Institute for LIfe Sciences
Research groups
Stress and ageing
Understanding the molecular mechanisms of ageing, focusing on the interconnection between stress and premature cellular senescence
Immunity and viruses
The APOBEC3-mediated innate immune response: antiviral activity and role in human cancer
Viral infections at the human-animal interface
Exploring epidemiological and molecular aspects of viral infections at the human-animal interface
Radiobiology and radiation therapy research
Understanding biological response to radiation and improving radiation therapy
Molecular cancer biology
Understanding the molecular mechansims of cancer drug resistance
Biology of intracellular trafficking
Unravelling the underlying causes and consequences of lysosomal storage disorders and other lysosome-associated diseases
Cells and Tissues
Exploring normal skin biology and cutaneous pathology
Genetic regulation of gene expression
Understanding how a single genome can encode the blueprint of a complex organism with highly differentiated cell-and tissue-types
Lysosomal function and dysfunction
Investigating lysosomal biogenesis and physiology
Neurodegeneration and regeneration
Understanding the physiopathology of neurodegenerative diseases in animal models & development of stem cell therapies for neurodegenerative diseases
Functions of MAGE / BOD1 proteins
Unraveling the functions of Melanoma Antigen (MAGE) and Biorientation Of Chromosomes In Cell Division 1(BOD1) proteins using knockout mouse models
Organelle (dys)function
Exploring the biology of mitochondria and other organelles, as well as their dysfunction in mammalian cell responses related to metabolism, obesity, stem cell differentiation, infection by intracellular bacteria, cancer cell irradiations…
Organelle (dys)function
Exploring the biology of mitochondria and other organelles, as well as their dysfunction in mammalian cell responses related to metabolism, obesity, stem cell differentiation, infection by intracellular bacteria, cancer cell irradiations…
Tumor hypoxia
Understanding the molecular mechanisms of cancer cell resistance to chemotherapy and radiation therapy
Dynamics of membranes and endocytosis
Unconventional endocytosis and its pathophysiological functions: unravelling the molecular mechanisms for their exploitation as pharmacological targets in cancer
Radiobiology and radiation therapy research | Biomaterials
Understanding biological response to radiation and improving radiation therapy | Engineering materials for biomedical applications
Ethology and animal welfare
Understanding behaviour of domestic and laboratory animals
Structural biological chemistry and structure-based drug design
Gaining knowledge about the 3D structure of protein targets to accelerate new drug discovery for the treatment of cancer and infectious diseases
Glycoscience and new drug design
Mechanistic and inhibition studies of essential enzymes involved in bacterial cell wall biosynthesis and colonization processes
Computer-aided and fragment-based drug design
Discovery of new therapeutic agents using computer-aided and fragment-based drug design approaches
