NAmur Research Institute for LIfe Sciences
Steve Lanners
Synthetic organic chemistry
Prof. Steve Lanners PhD
UNamur, Department of chemistry, Unit of organic chemistry (UCO), Laboratory of Synthetic Organic Chemistry (COS)
Member of the Namur Institute of Structured Matter (NISM)
Member of the Namur Medicine & Drug Innovation Center (NAMEDIC)
Research portal UNamur | ORCID | LinkedIn
Expertise and research interests
Group members
PhD students: Pierre Delmée, Loris Locquet and Amandine Traina
Research projects
- ONGOING Structure-based drug design and synthesis of selective smallmolecular- weight inhibitors of FXIIa, an attractive target from the intrinsic coagulation cascade. Ongoing PhD thesis by Amandine Traina. Under co-supervision by Prof. Steve Lanners (promoter) and Dr. Lionel Pochet (co-promoter).
- ONGOING Development of new methodologies for the synthesis of taxpropellane and canataxpropellane. Ongoing PhD thesis by Pierre Delmée.
- ONGOING Towards the Total Synthesis of Arteminolide A. Ongoing PhD thesis by Loris Locquet.
Selected publications
Jeanmart L, Mambourg K, Hanquet G, Lanners S. The Diels-Alder reaction of 1,4-quinones in hexafluoroisopropanol. Arkivoc. 2024 (5), art. no. 202312140.
Mambourg K, Tumanov N, Henon G, Lanners S, Garcia-Ladona J, Wouters J. Crystal structures of two alanyl-piperidine analogues. Acta Crystallogr E Crystallogr Commun. 2021 Oct 13;77(Pt 11):1095-1098.
Mambourg K, Bodart L, Tumanov N, Lanners S, Wouters J. Synthesis, crystal structure and conformational analysis of an unexpected [1,5]dithiocine product of aminopyridine and thiovanillin. Acta Crystallogr C Struct Chem. 2020 Mar 1;76(Pt3):205-211.
Balti M, Plas A, Meinguet C, Haufroid M, Thémans Q, Efrit ML, Wouters J, Lanners S. Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3607-3610.
Hanquet G, Salom-Roig X, Lanners S. New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides. Chimia (Aarau). 2016;70(1-2):20-8.
