NAmur Research Institute for LIfe Sciences
Completed PhD theses in the area of MEDICINAL CHEMISTRY
Site-selective functionalisation of antibody Glycans for biomedical applications
PhD thesis defended by Léa CHARTIER (Prof. Stéphane VINCENT) - 01/07/2022
Differentiation and Encapsulation of ß-like cells for the treatment of type 1 Diabetes Mellitus
PhD thesis defended by Myriam NEUMANN (Prof. Bao-Lian SU and Prof. Thierry ARNOULD) - 27/06/2022
Small molecules as therapeutic options in Parkinson’s disease: case of modulators of UCH-L1 and GLP-1 receptor
PhD thesis defended by Kalina MAMBOURG (Prof. Johan WOUTERS) - 31/03/2022
Structural and inhibition study of phosphoserine phosphatase (SerB2) from Mycobacterium tuberculosis
PhD thesis defended by Marie HAUFROID (Prof. Johan WOUTERS) - 25/03/2022
Towards the total synthesis of momilactones: asymmetric Diels-Alder reactions of quinones and sulfinylquinones for the synthesis of terpenes
PhD thesis defended by Loïc JEANMART (Prof. Steve LANNERS) - 08/12/2021
Synthesis and biological evaluations of novel pillar[5]arene conjugates
PhD thesis defended by Whenzhang CHEN (Prof. Stéphane VINCENT) - 27/10/2021
Drug-drug cocrystallization or salt formation as an alternative to combination drugs: a case study on clofazimine
PhD thesis defended by Laurie BODART (Prof. Johan WOUTERS) - 20/09/2021
Design and Synthesis of Phenylguanidine-Based and Benzamidine-Based FXIIa Inhibitors
PhD thesis defended by François SIMON (Prof. Steve LANNERS) - 18/12/2020
Synthesis and characterization of novel glycogold nanoparticles as antibiofilm and antibacterial agents
PhD thesis defended by Tao WANG (Prof. Stéphane VINCENT) - 28/10/2020
Characterization of the anticancer properties of new hydroxamate-based histone deactylase inhibitors
PhD thesis defended by Manon LERNOUX (Prof. Carine MICHIELS) - 22/11/2019
Potentialisation des chimiothérapies conventionnelles par la découverte de chimiosensibilisants actifs en hypoxie ou agissant sur la protéine VKORC1
PhD thesis defended by Sébastien MARX (Prof. Johan WOUTERS) - 25/10/2019
Synthesis of Heptose Mono- and Bisphosphate Analogues as Modulators of the Bacterial Innate Immunity and Inhibitors of the Bacterial Lipopolysaccharide
PhD thesis defended by Lina LIANG (Prof. Stéphane VINCENT) - 24/10/2019
Structural and functional approach of the first enzyme of the serine synthesis pathway: PHGDH a potential target for cancer treatment
PhD thesis defended by Quentin THEMANS (Prof. Johan WOUTERS) - 18/10/2019
Structural and functional characterization of the transmembrane protein 45A (TMEM45A) in triple negative breast cancers
PhD thesis defended by Thomas DAL MASO (Prof. Johan WOUTERS) - 04/10/2019
Influence des lipides de la membrane plasmique sur la structure et la fonction du récepteur opioïde µ par dynamique moléculaire gros grains
PhD thesis defended by Marie-Ange ANGLADON (Prof. Daniel VERCAUTEREN) - 01/07/2019
Photochromic multicomponent crystalline materials based on N-salicylideneanilines
PhD thesis defended by Andrea CARLETTA (Prof. Johan WOUTERS) - 25/04/2019
Synthesis of unprecedented electron-deficient exo-glycals targeting the Mycobacterium tuberculosis cell wall
PhD thesis defended by Christophe FREDERIC (Prof. Stéphane VINCENT) - 19/12/2018
Development of new debenzylative cyclization reactions and de novo synthesis of difluorinated glycomimetics
PhD thesis defended by Julien DELBROUCK (Prof. Stéphane VINCENT) - 20/11/2018
Synthetic derivatives of natural polyphenols targeting the mycobacterial cell wall
PhD thesis defended by Sydney VILLAUME (Prof. Stéphane VINCENT) - 15/10/2018
Synthèse de gamma-lactones et gamma-lactames beta-substituées en flux continu
PhD thesis defended by Stéphane COLLIN (Prof. Steve LANNERS) - 06/04/2018
Etude structurale d’imines et de phtalimides obtenus par mécanosynthèse
PhD thesis defended by Jean DUBOIS (Prof. Johan WOUTERS) - 24/11/2017
Discovery of novel inhibitors targeting the mycobacterial cell wall
PhD thesis defended by Jian FU (Prof. Stéphane VINCENT) - 06/10/2017
Discovery of inhibitors of the bacterial lipopolysaccharide as anti-virulence agents
PhD thesis defended by Huixiao FU (Prof. Stéphane VINCENT) - 05/10/2017
Design, synthesis and evaluation of coagulation FXIIa, inhibitors as potential antithrombotic agents
PhD thesis defended by Charlotte BOUCKAERT (Dr. Lionel POCHET) - 16/05/2017
Structural study of non-nucleoside inhibitors of DNA (cytosine-5) methyltransferases
PhD thesis defended by Grégoire RONDELET (Prof. Johan WOUTERS) - 13/12/2016
Towards the total synthesis of L-783,277
PhD thesis defended by Thanh Vy HOANG (Prof. Steve LANNERS) - 29/01/2016
On the intrinsic flexibility of the µ opioid receptor through multiscale modeling approaches
PhD thesis defended by Mathieu FOSSEPRE (Prof. Daniel VERCAUTEREN) - 20/01/2016
Conception, synthèse, caractérisation, évaluation pharmacologique et études in vivo de dérivés de l'harmine en tant que nouvelles molécules aux propriétés anticancéreuses
PhD thesis defended by Céline MEINGUET (Prof. Johan WOUTERS) - 25/09/2015
Etude des effets cytotoxiques de la pectine de Citrus fragmentée sur des cellules cancéreuses et identification d'une molécule active
PhD thesis defended by Lionel LECLERE (Prof. Carine MICHIELS) - 24/03/2014
