Completed PhD theses (all areas)
Identification, characterization, and optimization of fragment hits against coagulation factor XIIa supported by affinity capillary electrophoresis and biochemical assay
PhD thesis defended by Clara DAVOINE (Prof. Lionel POCHET & Prof. Marianne FILLET) - 25/04/2023
Development of the FibWave, an improved clot waveform analysis for the assessment of hemostasis
PhD thesis defended by Jonathan EVRARD (Prof. Jonathan DOUXFILS) - 11/04/2023
Study of the mechanisms leading to mitochondrial fragmentation and mitophagy in Brucella-infected cells and analysis of its functional consequences
PhD thesis defended by Jérémy VERBEKE (Prof. Thierry ARNOULD & Prof. Xavier DE BOLLE) - 30/03/2023
Smooth lipopolysaccharide biosynthesis, unipolar growth and disulfide bond formation in Brucella abortus cell envelope
PhD thesis defended by Caroline SERVAIS (Prof. Xavier DE BOLLE) - 27/02/2023
Characterization of the oligometric interface of Lactate Dehydrogenase-B (LDH-B) through crystallographic and molecular dynamics approaches
PhD thesis defended by Mégane VAN GYSEL (Prof. Johan WOUTERS) - 20/02/2023
Development of carbohydrate analogues as mechanistic probe for the characterization of galactofuranoside hydrolase
PhD thesis defended by Loïc CHENE (Prof. Stéphane VINCENT) - 25/01/2023
Analyse de l'implication de récepteurs multiples des interleukines 4 et 13 dans la dermatite atopique
PhD thesis defended by Audrey PROGNEAUX (Prof. Yves POUMAY) - 16/12/2022
Plasticity of human indoleamine-2,3-dioxygenases 1 and 2 through a structural approach combining crystallography and Molecular Dynamics studies
PhD thesis defended by Manon MIRGAUX (Prof. Johan WOUTERS) - 16/11/2022
Deciphering the senescent phenotype induced by radiotherapy, protontherapy and PARP inhibitors in cancer cell lines
PhD thesis defended by Camille HUART (Prof. Carine MICHIELS) - 28/10/2022
Synthesis of Heptose mimetics as inhibitors of bacterial enzymes or modulators of inflammation
PhD thesis defended by Jun CAO (Prof. Stéphane VINCENT) - 20/10/2022
Biophysical and enzymological exploration of Mycobacterium tuberculosis phosphoserine phosphatase SerB2 self-assembly and regulation by L-serine
PhD thesis defended by Elise PIERSON (Prof. Johan WOUTERS) - 03/10/2022
The APOBEC3B cytidine deaminase is an adenovirus restriction factor
PhD thesis defended by Noémie LEJEUNE (Prof. Nicolas GILLET) - 30/08/2022
Overcoming issues in plasmatic evaluation of direct Factor Xa inhibitors
PhD thesis defended by Romain SIRIEZ (Prof. Jonathan DOUXFILS) - 06/07/2022
Site-selective functionalisation of antibody Glycans for biomedical applications
PhD thesis defended by Léa CHARTIER (Prof. Stéphane VINCENT) - 01/07/2022
Differentiation and Encapsulation of ß-like cells for the treatment of type 1 Diabetes Mellitus
PhD thesis defended by Myriam NEUMANN (Prof. Bao-Lian SU and Prof. Thierry ARNOULD) - 27/06/2022
Small molecules as therapeutic options in Parkinson’s disease: case of modulators of UCH-L1 and GLP-1 receptor
PhD thesis defended by Kalina MAMBOURG (Prof. Johan WOUTERS) - 31/03/2022
Evaluation of the shear wave elastography in assessing the biomechanical properties of the patellar tendon in an ovine model
PhD thesis defended by Dr. Françoise KAYSER (Prof. Jean-Michel VANDEWEERD) - 28/03/2022
Structural and inhibition study of phosphoserine phosphatase (SerB2) from Mycobacterium tuberculosis
PhD thesis defended by Marie HAUFROID (Prof. Johan WOUTERS) - 25/03/2022
Association of cardiovascular occlusive events with BCR-ABL tyrosine kinase therapy - Identification, understanding and prediction
PhD thesis defended by Hélène HAGUET (Prof. Jonathan DOUXFILS - Prof. François MULLIER) - 11/02/2022
Histidine biosynthesis, cell separation and copper resistance in Brucella abortus
PhD thesis defended by Agnès ROBA (Prof. Xavier DE BOLLE) - 04/02/2022
Spatial analysis of health inequalities in Dakar, Senegal
PhD thesis defended by Assane GADIAGA (Prof. Catherine LINARD) - 31/01/2022
La matrice extracellulaire épidermique : caractérisation de TSG-6 et de l'hyaluronan en contexte inflammatoire
PhD thesis defended by Céline EVRARD (Prof. Yves POUMAY) - 21/01/2022
Interactions Between the Outer Membrane and the Peptidoglycan in Brucella abortus
PhD thesis defended by Pierre GODESSART (Prof. Xavier DE BOLLE) - 17/12/2021
Towards the total synthesis of momilactones: asymmetric Diels-Alder reactions of quinones and sulfinylquinones for the synthesis of terpenes
PhD thesis defended by Loïc JEANMART (Prof. Steve LANNERS) - 08/12/2021
Hyaluronan metabolism in naked mole-rat
PhD thesis defended by Delphine DEL MARMOL (Prof. Bruno FLAMION) - 05/11/2021
Synthesis and biological evaluations of novel pillar[5]arene conjugates
PhD thesis defended by Whenzhang CHEN (Prof. Stéphane VINCENT) - 27/10/2021
Phenotypic adaptation and regulatory response to copper stress in Cupriavidus metallidurans
PhD thesis defended by Laurens MAERTENS (Prof. Jean-Yves MATROULE) - 25/10/2021
Study of UVB-stress-induced premature senescence in normal human epidermal keratinocytes
PhD thesis defended by Emilie BAUWENS (Dr. Florence CHAINIAUX) - 24/09/2021
Drug-drug cocrystallization or salt formation as an alternative to combination drugs: a case study on clofazimine
PhD thesis defended by Laurie BODART (Prof. Johan WOUTERS) - 20/09/2021
Study of the effects of cycling hypoxia on macrophages and on the interaction between macrophages and endothelial cells : role in the promotion of tumor inflammation
PhD thesis defended by Victor DELPRAT (Prof. Carine MICHIELS) - 24/08/2021