Completed PhD theses in the area of CANCER

Enhancing the immunogenicity of macrophages in radiation therapy using gold nanoparticles

PhD thesis defended by Shalini IYER (Prof. Anne-Catherine HEUSKIN & Prof. Carine MICHIELS) - 12/08/2025

The FLASH effect in 2D and 3D in vitro models upon proton irradiation

PhD thesis defended by Andrea SCARMELOTTO (Prof. Stéphane LUCAS) - 27/06/2025

Endophilin A3-mediated clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation

PhD thesis defended by Shiqiang XU (Prof. Henri-François RENARD & Prof. Pierre MORSOMME) - 11/03/2025

Investigation of the ABCB5β transporter dimerization status

PhD thesis defended by Louise GERARD (Prof. Jean-Pierre GILLET) - 26/06/2024

Bench and bed optimization of radiation therapy of head and neck cancer

PhD thesis defended by Dr. Eléonore LONGTON (Prof. Carine MICHIELS & Prof. Jean-François DAISNE) - 19/04/2024

Study of the subcellular localization of the human ATP-binding cassette transporter isoform, ABCB5β, expressed in melanoma.

PhD thesis defended by Adriana DIAZ (Prof. Jean-Pierre GILLET) - 27/10/2023

Study of the immunomodulatory effects of irradiation on human papillomavirus-driven vs. carcinogen-driven head and neck squamous cell carcinoma

PhD thesis defended by Christoph SCHIFFLERS (Prof. Carine MICHIELS & PD Angelika RIEMER) - 15/09/2023

Identification of genes implicated in the resistance to treatment in Glioblastoma: focus on intracellular trafficking pathway

PhD thesis defended by Jia-Wei CHEN (Prof. Carine MICHIELS & Prof. Anne-Catherine HEUSKIN) - 07/09/2023

Characterization of the oligometric interface of Lactate Dehydrogenase-B (LDH-B) through crystallographic and molecular dynamics approaches

PhD thesis defended by Mégane VAN GYSEL (Prof. Johan WOUTERS) - 20/02/2023

Deciphering the senescent phenotype induced by radiotherapy, protontherapy and PARP inhibitors in cancer cell lines

PhD thesis defended by Camille HUART (Prof. Carine MICHIELS) - 28/10/2022

The APOBEC3B cytidine deaminase is an adenovirus restriction factor

PhD thesis defended by Noémie LEJEUNE (Prof. Nicolas GILLET) - 30/08/2022

Association of cardiovascular occlusive events with BCR-ABL tyrosine kinase therapy - Identification, understanding and prediction

PhD thesis defended by Hélène HAGUET (Prof. Jonathan DOUXFILS - Prof. François MULLIER) - 11/02/2022

Study of the effects of cycling hypoxia on macrophages and on the interaction between macrophages and endothelial cells : role in the promotion of tumor inflammation

PhD thesis defended by Victor DELPRAT (Prof. Carine MICHIELS) - 24/08/2021

Characterization of the migratory phenotype of cancer cells selected on IGDQ expressing surface: “PACMAN" project

PhD thesis defended by Sophie AYAMA (Prof. Carine MICHIELS) - 05/07/2021

Role of DNA methylation and CpG sites in the viral telomerase RNA promoter during Gallid herpesvirus type 2 induced lymphomagenesis

PhD thesis defended by Srdan PEJAKOVIC (Prof. Benoît MUYLKENS) - 29/09/2020

Potentialisation des chimiothérapies conventionnelles par la découverte de chimiosensibilisants actifs en hypoxie ou agissant sur la protéine VKORC1

PhD thesis defended by Sébastien MARX (Prof. Johan WOUTERS) - 25/10/2019

Involvement of the ABCB5 transporter in the development and progression of cutaneous melanoma

PhD thesis defended by Géraldine SANA (Prof. Jean-Pierre GILLET) - 23/10/2019

Structural and functional approach of the first enzyme of the serine synthesis pathway: PHGDH a potential target for cancer treatment

PhD thesis defended by Quentin THEMANS (Prof. Johan WOUTERS) - 18/10/2019

Study of the reciprocal interaction between replicative senescent or UVB-SIPS fibroblasts and squamous cell carcinoma cell lines at different stages of tumorigenesis

PhD thesis defended by Marie TOUTFAIRE (Dr. Florence CHAINIAUX) - 09/11/2018

Completed PhD theses in the area of CANCER

Enhancing the immunogenicity of macrophages in radiation therapy using gold nanoparticles

The FLASH effect in 2D and 3D in vitro models upon proton irradiation

Endophilin A3-mediated clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation

Investigation of the ABCB5β transporter dimerization status

Bench and bed optimization of radiation therapy of head and neck cancer

Study of the subcellular localization of the human ATP-binding cassette transporter isoform, ABCB5β, expressed in melanoma.

Study of the immunomodulatory effects of irradiation on human papillomavirus-driven vs. carcinogen-driven head and neck squamous cell carcinoma

Identification of genes implicated in the resistance to treatment in Glioblastoma: focus on intracellular trafficking pathway

Characterization of the oligometric interface of Lactate Dehydrogenase-B (LDH-B) through crystallographic and molecular dynamics approaches

Deciphering the senescent phenotype induced by radiotherapy, protontherapy and PARP inhibitors in cancer cell lines

The APOBEC3B cytidine deaminase is an adenovirus restriction factor

Association of cardiovascular occlusive events with BCR-ABL tyrosine kinase therapy - Identification, understanding and prediction

Study of the effects of cycling hypoxia on macrophages and on the interaction between macrophages and endothelial cells : role in the promotion of tumor inflammation

Characterization of the migratory phenotype of cancer cells selected on IGDQ expressing surface: “PACMAN" project

Role of DNA methylation and CpG sites in the viral telomerase RNA promoter during Gallid herpesvirus type 2 induced lymphomagenesis

Hybrid gold nanoparticles coated with organic polymers and antibodies as platform for cancer theranostics

Study of the putative role of MPV17 in cancer cell proliferation

Characterization of the anticancer properties of new hydroxamate-based histone deactylase inhibitors

Potentialisation des chimiothérapies conventionnelles par la découverte de chimiosensibilisants actifs en hypoxie ou agissant sur la protéine VKORC1

Involvement of the ABCB5 transporter in the development and progression of cutaneous melanoma

Structural and functional approach of the first enzyme of the serine synthesis pathway: PHGDH a potential target for cancer treatment

Structural and functional characterization of the transmembrane protein 45A (TMEM45A) in triple negative breast cancers

Theoretical and experimental study of the proton induced secondary electron emission from nanometer gold targets

Implication de la protéine TMEM45A dans la chimiorésistance

Contribution to the improvement of radiotherapy treatments driven by nanotechnology

Study of the reciprocal interaction between replicative senescent or UVB-SIPS fibroblasts and squamous cell carcinoma cell lines at different stages of tumorigenesis

Study of the epigenetic silencing of a host microRNA in Marek’s disease

Unravelling the effects of proton irradiation on macrophages in cancer

Structural study of non-nucleoside inhibitors of DNA (cytosine-5) methyltransferases

Functionalized Fe-filled Carbon Nanotubes for Cancer Theranostics